జీర్ణకోశ & జీర్ణ వ్యవస్థ

నైరూప్య

Gastrointestinal Stromal Tumor: A Cytologist’s Perspective

T Santosh, Kanchan Kothari, Pragati Sathe and Prachi Gholap

Introduction: Gastro-intestinal stromal tumors are mesenchymal tumors they have a unique immunophenotype, expressing c-KIT (CD117), DOG-1 and CD34 in most cases. Most commonly occurring in small intestine and stomach.

Case report: We report a case of EUS guided FNA from gastric mass in a 60 year old patient. Cytology showed cellular smears with palisade of tumor cells and blunt end spindle cells.

Discussion: GIST is very difficult to differentiate from other benign tumors i.e. leiomyoma and schwannoma. EUS guided FNA can be a very useful tool in approaching deep seated intra-abdominal lesion with ease. It also helps in diagnosis and treatment of the disease in a better way.