జీర్ణకోశ & జీర్ణ వ్యవస్థ

నైరూప్య

Gastro-Entero-Pancreatic Neuroendocrine Tumors (GEP-Nets): A Review

Chuangqi Chen, Xiaojiang Yi and Yulong He

Introduction: The diagnosis of Gastro-entero-pancreatic Neuroendocrine Tumors (GEP-NETs) is currently a common event and it has showed the highest incidence of NETs. The majority of this lesion are well differentiated and with only a minority performing a malignant behavior. However, it poses a significant challenge to diagnosis especially for the assessment of the malignant potential of well differentiated types and many aspects of the management remain unclear and controversial. Recently, some new progresses of this disease have been put into clinical practice and some are still on trail.

Methods: We will present a review of GEP-NETs on classification, pathology, clinical manifestation, biomarkers, management and follow-up.

Conclusion: This review aims to provide some new understanding of pathologic classification and clinical diagnosis in GEP-NETs. On the basis of patients’ individual condition, comprehensive treatment options should be carried out to achieve a better therapeutic effect and improve the quality of life.