మా గ్రూప్ ప్రతి సంవత్సరం USA, యూరప్ & ఆసియా అంతటా 3000+ గ్లోబల్ కాన్ఫరెన్స్ ఈవెంట్లను నిర్వహిస్తుంది మరియు 1000 కంటే ఎక్కువ సైంటిఫిక్ సొసైటీల మద్దతుతో 700+ ఓపెన్ యాక్సెస్ జర్నల్లను ప్రచురిస్తుంది , ఇందులో 50000 మంది ప్రముఖ వ్యక్తులు, ప్రఖ్యాత శాస్త్రవేత్తలు ఎడిటోరియల్ బోర్డ్ సభ్యులుగా ఉన్నారు.
ఎక్కువ మంది పాఠకులు మరియు అనులేఖనాలను పొందే ఓపెన్ యాక్సెస్ జర్నల్స్
700 జర్నల్స్ మరియు 15,000,000 రీడర్లు ప్రతి జర్నల్ 25,000+ రీడర్లను పొందుతున్నారు
Jayaprakash Sreenarasimhaiah
Background: Dysplastic Barrett's esophagus is the precursor to esophageal adenocarcinoma. While traditional therapy has included surgical resection, several endoscopic ablation techniques have become well-established. The newest of these modalities is cryospray ablation using liquid nitrogen.
Objective: To determine efficacy of cryospray ablation therapy in eradication of Barrett's mucosa and dysplastic tissue as well as the durability of these outcomes.
Methods: A retrospective analysis of 33 consecutive patients who underwent endoscopic cryoablation therapy was performed. Patients were followed at 8 weeks, 6 months, and annually following completion of ablation. Biopsies were taken.
Results: A mean of 2.4 sessions (range 1-4) was performed with a mean follow-up of 12.5 months (range 6-36). 100% of patients with low-grade dysplasia achieved complete eradication of dysplasia at a minimum follow-up of 6 months. 95% of highgrade dysplasia was eradicated at 6 months with 5% having persistent focal low-grade dysplasia. In 9% of cases, intramucosal carcinoma was also treated successfully with cryospray ablation therapy. Overall stricture rate was 3% following ablation therapy. No perforations or other serious complications occurred
Conclusions: Cryoablation therapy offers an effective minimimally-invasive method to treat dysplastic Barrett's esophagus as well as some early intramucosal adenocarcinoma. There is minimal morbidity from this procedure and has potentially durable results at follow-up endoscopic surveillance.