మా గ్రూప్ ప్రతి సంవత్సరం USA, యూరప్ & ఆసియా అంతటా 3000+ గ్లోబల్ కాన్ఫరెన్స్ ఈవెంట్లను నిర్వహిస్తుంది మరియు 1000 కంటే ఎక్కువ సైంటిఫిక్ సొసైటీల మద్దతుతో 700+ ఓపెన్ యాక్సెస్ జర్నల్లను ప్రచురిస్తుంది , ఇందులో 50000 మంది ప్రముఖ వ్యక్తులు, ప్రఖ్యాత శాస్త్రవేత్తలు ఎడిటోరియల్ బోర్డ్ సభ్యులుగా ఉన్నారు.
ఎక్కువ మంది పాఠకులు మరియు అనులేఖనాలను పొందే ఓపెన్ యాక్సెస్ జర్నల్స్
700 జర్నల్స్ మరియు 15,000,000 రీడర్లు ప్రతి జర్నల్ 25,000+ రీడర్లను పొందుతున్నారు
Dhruv Singhal
Metabolic regulation and obesity caused by overeating are thought to be major risk factors for breast cancer. Both obesity and breast cancer can be traced back to early stages of human development. A natural is flavone found in soybean products called genistein (GE) has been linked to a lower risk of breast cancer and other metabolic disorders. Our review expected to decide the impacts of maternal openness to soybean dietary GE on avoidance of over nutrition-prompted bosom malignant growth further down the road and investigate possible components in various mouse models. By significantly reducing the high-fat diet-induced body fat accumulation, lipid panel abnormalities, and glucose intolerance in the offspring of mice, our findings demonstrated that maternal dietary GE treatment improved metabolic functions in the offspring. Importantly, exposure to GE in the mother’s diet effectively delayed the development of female offspring’s simulated mammary tumors caused by a high-fat diet. We discovered that, at least partially through regulation of the offspring’s gut microbiome, bacterial metabolites, and epigenetic profiles, maternal GE may exert its chemo preventive effects by affecting essential regulatory gene expression in control of metabolism, inflammation, and tumor development. Through dynamically influencing the interaction between early-life gut micro biota, key microbial metabolite profiles, and offspring epigenome, our findings suggest that maternal GE consumption is an effective intervention approach leading to early-life prevention of obesity-related metabolic disorders and breast cancer later in life.